We are living with a lot of diseases related to fevers with different names like Chikungunya fever, West Nile fever, rheumatic fever, Relapsing fever, Rat-bite fever (sodoku), Haver hill fever, Dengue fever, Typhoid fever, Scarlet fever, Viral hemorrhagic fever, etc. In COVID -19 up to 85% of patients have no fever. Why up to 80% of patients with the COVID -19 (SARS-CoV-2) virus have no fever? Is it because there is no need for the care of fever or is it because the disease is free of signals or symptoms?

This paper discusses the statistical measurement of the impact of COVID-19 major emergencies on farmers economic income in Hubei Province. Hubei Province was selected as the object of analysis, and five data of total output value of agriculture, forestry, animal husbandry, fishery and per capita disposable income of farmers in Hubei Province from the first quarter of 2013 to the second quarter of 2020 were collected by using the Internet. Since all the collected data were macroeconomic data, these data were taken the logarithm to meet the economic significance. The per capita disposable income of farmers was taken as the response variable, and the main factors affecting farmers income were obtained by factor analysis. Livestock husbandry and fishery industries were the main industries in Hubei Province. Then the score of factor analysis were taken as explained variable to establish regression model composed of influencing factors. This paper use the multiple linear regression, support vector regression to fitting and forecasting data, ARIMA model of time series analysis, introduced at the same time, through the AIC model choice, with the first quarter of 2013 to 2019 in the second quarter fitting training, backward prediction two quarters, and three or four quarter of 2019 compared with the real data, through to the predicted results of the sequence diagram and evaluation index model to compare the mean square error (RMSE). Three models predict per capita disposable income of farmers in the first and second quarter of 2020. It has been found that performance better ARIMA model in the model compare is worse than before, and three kinds of predicted values are higher than the real value of the model, showed the outbreak to the influence of the agricultural economy in hubei province is serious. On this basis, taking into account the characteristics of geomorphic climate in Hubei province, the constructive suggestions are put forward.

Background: Colorectal cancer is a common and lethal cancer worldwide, In the UK, it is the second most common cause of cancer death. 5% of UK population is at risk of colorectal carcinoma during lifetime. 30% of patients with colorectal cancer present with a metastatic disease. Detecting colorectal cancer is challenging patients may present with slight symptoms or asymptomatic. By the time patients becomes symptomatic, the cancer may be more advanced. Therefore, screening for colorectal cancer is recommended for people at average risk. Method: All patients diagnosed with colorectal cancer at the Luton and Dunstable University Hospital UK from January 2015 through December 2019 were retrospectively identified from the referral database created by colorectal specialist nurses in the colorectal service. Data were retrieved by detailed review of the hospital case notes, ICE/Evolve (Computer database for investigations and correspondence) including endoscopy; radiographic imaging; operative course and cancer follow up. Results: In the study period 976 patients were diagnosed with colorectal cancer, Male 52.6% (513) Female 47.4% (463). The mean age of 74.14 years (range, 25 to 101). Sixty six 6.76% patients were excluded from the study, therefore the percentages of studied participant were Male 53 % (482) and Female 47 % (428) ratio 1: 1.12. Incidence of colorectal cancer among young adult was low 1.75% (16) up to 39 years of age) and 94.61% are diagnosed in people over the age of 50 years, 60.43% are diagnosed in people aged 70 or over. Conclusion: Increasing awareness of the symptoms and signs of colorectal cancer be helpful and beneficial. Establish integrated care pathways, centralization of complex procedures and comparison of international cancer outcomes.

Anaphylaxis during anesthesia is an unforeseeable and potentially life threatening syndrome that is dose independent. Ketamine is a widely used hypnotic for procedural sedation in the emergency department, in anesthesia and intensive care units (ICU). It is popularly employed for both children and adult patients. Though, dose dependent adverse effects of ketamine have been described, the hypersensitive reactions with the same are extremely rare. We are hereby presenting a case of an allergic reaction and isolated bradycardia with ketamine, given as intravenous monotherapy in a patient with no previous history of atopic disease. Our article aims at reminding all the medical professionals to never let a drug (however commonly used) throw away caution, be vigilant to timely diagnose an adverse drug reaction (even the most infrequent and rare) and be prepared to tackle the worst with the necessary supportive measures like hemodynamic support and advanced airway procedures.